                         SEQUENCE LISTING



<110>  Ghosh, Malabika 

      Tang, Y. Tom 

      Liu, Chenghua 

      Drmanac, Radoje 



<120>  Methods and Materials Relating to Prokineticin-like Polypeptides and Polynucleotides



<130>  HYS-45 CIP/PCT



<140>  Not yet assigned 

<141>  2002-11-01



<150>  09/552,929

<151>  2000-04-18



<150>  09/770,160

<151>  2001-01-26



<150>  PCT/US01/08656

<151>  2001-04-18



<150>  60/343,902

<151>  2001-11-02



<160>  21    



<170>  PatentIn version 3.1



<210>  1

<211>  322

<212>  DNA

<213>  Homo sapiens



<220>

<221>  misc_feature

<222>  (1)..(322)

<223>  n=a,t,c,or g



<400>  1
gaagcaaaag gaaaaaggag gttccatttt ttgggcggag gatgcatcac acttgcccat     60

gtctgccagg cttggcctgt ttacggactt catttaaccg atttatttgt ttagcccaaa    120

agtaatcgct ctggagtaga aaccaaatgt gaatagccac atcttacctg taaagtctta    180

cttgtgattg tgccaaacaa aaaatgtgcc agaaagaaat gctcttgctt cctcaacttt    240

ccaagtaaca tttttatctt tgatttgtaa atgannnnnn nnnnnnnnna tcgaaagaaa    300

attttacttt tggataaaaa ta                                             322


<210>  2

<211>  381

<212>  DNA

<213>  Homo sapiens



<400>  2
atgaggagcc tgtgctgcgc cccactcctg ctcctcttgc tgctgccgcc gctgctgctc     60

acgccccgcg ctggggacgc cgccgtgatc accggggctt gtgacaagtc ccaatgtggt    120

ggaggcatgt gctgtgctgt cagtatctgg gtcagcataa ggatttgcac acctatgggc    180

aaactgggag acagctgccc actgactcgt aaaaacaatt ttggaaatgg aaggcaggaa    240

agaagaaaga ggaagagaag caaaaggaaa aaggaggttc cattttttgg gcggaggatg    300

catcacactt gcccatgtct gccaggcttg gcctgtttac ggacttcatt taaccgattt    360

atttgtttag cccaaaagta a                                              381


<210>  3

<211>  126

<212>  PRT

<213>  Homo sapiens



<400>  3

Met Arg Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Leu Leu Leu Thr Pro Arg Ala Gly Asp Ala Ala Val Ile Thr Gly 
            20                  25                  30          


Ala Cys Asp Lys Ser Gln Cys Gly Gly Gly Met Cys Cys Ala Val Ser 
        35                  40                  45              


Ile Trp Val Ser Ile Arg Ile Cys Thr Pro Met Gly Lys Leu Gly Asp 
    50                  55                  60                  


Ser Cys Pro Leu Thr Arg Lys Asn Asn Phe Gly Asn Gly Arg Gln Glu 
65                  70                  75                  80  


Arg Arg Lys Arg Lys Arg Ser Lys Arg Lys Lys Glu Val Pro Phe Phe 
                85                  90                  95      


Gly Arg Arg Met His His Thr Cys Pro Cys Leu Pro Gly Leu Ala Cys 
            100                 105                 110         


Leu Arg Thr Ser Phe Asn Arg Phe Ile Cys Leu Ala Gln Lys 
        115                 120                 125     


<210>  4

<211>  27

<212>  PRT

<213>  Homo sapiens



<400>  4

Met Arg Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Leu Leu Leu Thr Pro Arg Ala Gly Asp Ala 
            20                  25          


<210>  5

<211>  99

<212>  PRT

<213>  Homo sapiens



<400>  5

Ala Val Ile Thr Gly Ala Cys Asp Lys Ser Gln Cys Gly Gly Gly Met 
1               5                   10                  15      


Cys Cys Ala Val Ser Ile Trp Val Ser Ile Arg Ile Cys Thr Pro Met 
            20                  25                  30          


Gly Lys Leu Gly Asp Ser Cys Pro Leu Thr Arg Lys Asn Asn Phe Gly 
        35                  40                  45              


Asn Gly Arg Gln Glu Arg Arg Lys Arg Lys Arg Ser Lys Arg Lys Lys 
    50                  55                  60                  


Glu Val Pro Phe Phe Gly Arg Arg Met His His Thr Cys Pro Cys Leu 
65                  70                  75                  80  


Pro Gly Leu Ala Cys Leu Arg Thr Ser Phe Asn Arg Phe Ile Cys Leu 
                85                  90                  95      


Ala Gln Lys 
            


<210>  6

<211>  322

<212>  DNA

<213>  Homo sapiens



<220>

<221>  misc_feature

<222>  (1)..(322)

<223>  n=a,t,g, or c



<400>  6
gaagcaaaag gaaaaaggag gttccatttt ttgggcggag gatgcatcac acttgcccat     60

gtctgccagg cttggcctgt ttacggactt catttaaccg atttatttgt ttagcccaaa    120

agtaatcgct ctggagtaga aaccaaatgt gaatagccac atcttacctg taaagtctta    180

cttgtgattg tgccaaacaa aaaatgtgcc agaaagaaat gctcttgctt cctcaacttt    240

ccaagtaaca tttttatctt tgatttgtaa atgannnnnn nnnnnnnnna tcgaaagaaa    300

attttacttt tggataaaaa ta                                             322


<210>  7

<211>  40

<212>  PRT

<213>  Homo sapiens



<400>  7

Ser Lys Arg Lys Lys Glu Val Pro Phe Phe Gly Arg Arg Met His His 
1               5                   10                  15      


Thr Cys Pro Cys Leu Pro Gly Leu Ala Cys Leu Arg Thr Ser Phe Asn 
            20                  25                  30          


Arg Phe Ile Cys Leu Ala Gln Lys 
        35                  40  


<210>  8

<211>  19

<212>  PRT

<213>  Homo sapiens



<400>  8

Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro Pro Leu Leu 
1               5                   10                  15      


Leu Thr Pro 
            


<210>  9

<211>  17

<212>  PRT

<213>  Homo sapiens



<400>  9

Leu Leu Leu Leu Leu Leu Leu Pro Pro Leu Leu Leu Thr Pro Arg Ala 
1               5                   10                  15      


Gly 
    


<210>  10

<211>  21

<212>  PRT

<213>  Homo sapiens



<400>  10

Pro Pro Leu Leu Leu Thr Pro Arg Ala Gly Asp Ala Ala Val Ile Thr 
1               5                   10                  15      


Gly Ala Cys Asp Lys 
            20      


<210>  11

<211>  12

<212>  PRT

<213>  Homo sapiens



<400>  11

Ser Ile Arg Ile Cys Thr Pro Met Gly Lys Leu Gly 
1               5                   10          


<210>  12

<211>  17

<212>  PRT

<213>  Homo sapiens



<400>  12

Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro Pro Leu 
1               5                   10                  15      


Leu 
    


<210>  13

<211>  10

<212>  PRT

<213>  Homo sapiens



<400>  13

Cys Gly Gly Gly Met Cys Cys Ala Val Ser 
1               5                   10  


<210>  14

<211>  124

<212>  PRT

<213>  homo sapiens



<400>  14

Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro Pro Leu Leu Leu Thr 
1               5                   10                  15      


Pro Arg Ala Gly Asp Ala Ala Val Ile Thr Gly Ala Cys Asp Lys Asp 
            20                  25                  30          


Ser Gln Cys Gly Gly Gly Met Cys Cys Ala Val Ser Ile Trp Val Lys 
        35                  40                  45              


Ser Ile Arg Ile Cys Thr Pro Met Gly Lys Leu Gly Asp Ser Cys His 
    50                  55                  60                  


Pro Leu Thr Arg Lys Asn Asn Phe Gly Asn Gly Arg Gln Glu Arg Arg 
65                  70                  75                  80  


Lys Arg Lys Arg Ser Lys Arg Lys Lys Glu Val Pro Phe Phe Gly Arg 
                85                  90                  95      


Arg Met His His Thr Cys Pro Cys Leu Pro Gly Leu Ala Cys Leu Arg 
            100                 105                 110         


Thr Ser Phe Asn Arg Phe Ile Cys Leu Ala Gln Lys 
        115                 120                 


<210>  15

<211>  128

<212>  PRT

<213>  Mus musculus



<400>  15

Met Gly Asp Pro Arg Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Leu Leu Phe Thr Pro Pro Ala Gly Asp Ala Ala Val Ile Thr Gly Ala 
            20                  25                  30          


Cys Asp Lys Asp Ser Gln Cys Gly Gly Gly Met Cys Cys Ala Val Ser 
        35                  40                  45              


Ile Trp Val Lys Ser Ile Arg Ile Cys Thr Pro Met Gly Gln Val Gly 
    50                  55                  60                  


Asp Ser Cys His Pro Leu Thr Arg Lys Ser His Val Ala Asn Gly Arg 
65                  70                  75                  80  


Gln Glu Arg Arg Arg Ala Lys Arg Arg Lys Arg Lys Lys Glu Val Pro 
                85                  90                  95      


Phe Trp Gly Arg Arg Met His His Thr Cys Pro Cys Leu Pro Gly Leu 
            100                 105                 110         


Ala Cys Leu Arg Thr Ser Phe Asn Arg Phe Ile Cys Leu Ala Arg Lys 
        115                 120                 125             


<210>  16

<211>  105

<212>  PRT

<213>  Homo sapiens



<400>  16

Met Arg Gly Ala Thr Arg Val Ser Ile Met Leu Leu Leu Val Thr Val 
1               5                   10                  15      


Ser Asp Cys Ala Val Ile Thr Gly Ala Cys Glu Arg Asp Val Gln Cys 
            20                  25                  30          


Gly Ala Gly Thr Cys Cys Ala Ile Ser Leu Trp Leu Arg Gly Leu Arg 
        35                  40                  45              


Met Cys Thr Pro Leu Gly Arg Glu Gly Glu Glu Cys His Pro Gly Ser 
    50                  55                  60                  


His Lys Val Pro Phe Phe Arg Lys Arg Lys His His Thr Cys Pro Cys 
65                  70                  75                  80  


Leu Pro Asn Leu Leu Cys Ser Arg Phe Pro Asp Gly Arg Tyr Arg Cys 
                85                  90                  95      


Ser Met Asp Leu Lys Asn Ile Asn Phe 
            100                 105 


<210>  17

<211>  108

<212>  PRT

<213>  Homo sapiens



<400>  17

Met Arg Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Leu Leu Leu Thr Pro Arg Ala Gly Asp Ala Ala Val Ile Thr Gly 
            20                  25                  30          


Ala Cys Asp Lys Asp Ser Gln Cys Gly Gly Gly Met Cys Cys Ala Val 
        35                  40                  45              


Ser Ile Trp Val Lys Ser Ile Arg Ile Cys Thr Pro Met Gly Lys Leu 
    50                  55                  60                  


Gly Asp Ser Cys His Pro Leu Thr Arg Lys Val Pro Phe Phe Gly Arg 
65                  70                  75                  80  


Arg Met His His Thr Cys Pro Cys Leu Pro Gly Leu Ala Cys Leu Arg 
                85                  90                  95      


Thr Ser Phe Asn Arg Phe Ile Cys Leu Ala Gln Lys 
            100                 105             


<210>  18

<211>  80

<212>  PRT

<213>  Dendroaspis Polylepis Polylepis



<400>  18

Ala Val Ile Thr Gly Ala Cys Glu Arg Asp Leu Gln Cys Gly Lys Gly 
1               5                   10                  15      


Thr Cys Cys Ala Val Ser Leu Trp Ile Lys Ser Val Arg Val Cys Thr 
            20                  25                  30          


Pro Val Gly Thr Ser Gly Glu Asp Cys His Pro Ala Ser His Lys Ile 
        35                  40                  45              


Pro Phe Ser Gly Gln Arg Met His His Thr Cys Pro Cys Ala Pro Asn 
    50                  55                  60                  


Leu Ala Cys Val Gln Thr Ser Pro Lys Lys Phe Lys Cys Leu Ser Lys 
65                  70                  75                  80  


<210>  19

<211>  96

<212>  PRT

<213>  Bombina variegata



<400>  19

Met Lys Cys Phe Ala Gln Ile Val Val Leu Leu Leu Val Ile Ala Phe 
1               5                   10                  15      


Ser His Gly Ala Val Ile Thr Gly Ala Cys Asp Lys Asp Val Gln Cys 
            20                  25                  30          


Gly Ser Gly Thr Cys Cys Ala Ala Ser Ala Trp Ser Arg Asn Ile Arg 
        35                  40                  45              


Phe Cys Ile Pro Leu Gly Asn Ser Gly Glu Asp Cys His Pro Ala Ser 
    50                  55                  60                  


His Lys Val Pro Tyr Asp Gly Lys Arg Leu Ser Ser Leu Cys Pro Cys 
65                  70                  75                  80  


Lys Ser Gly Leu Thr Cys Ser Lys Ser Gly Glu Lys Phe Lys Cys Ser 
                85                  90                  95      


<210>  20

<211>  24

<212>  PRT

<213>  Homo sapiens



<400>  20

Met Arg Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Leu Leu Leu Thr Pro Arg Ala 
            20                  


<210>  21

<211>  129

<212>  PRT

<213>  Homo sapiens



<400>  21

Met Arg Ser Leu Cys Cys Ala Pro Leu Leu Leu Leu Leu Leu Leu Pro 
1               5                   10                  15      


Pro Leu Leu Leu Thr Pro Arg Ala Gly Asp Ala Ala Val Ile Thr Gly 
            20                  25                  30          


Ala Cys Asp Lys Asp Ser Gln Cys Gly Gly Gly Met Cys Cys Ala Val 
        35                  40                  45              


Ser Ile Trp Val Lys Ser Ile Arg Ile Cys Thr Pro Met Gly Lys Leu 
    50                  55                  60                  


Gly Asp Ser Cys His Pro Leu Thr Arg Lys Asn Asn Phe Gly Asn Gly 
65                  70                  75                  80  


Arg Gln Glu Arg Arg Lys Arg Lys Arg Ser Lys Arg Lys Lys Glu Val 
                85                  90                  95      


Pro Phe Phe Gly Arg Arg Met His His Thr Cys Pro Cys Leu Pro Gly 
            100                 105                 110         


Leu Ala Cys Leu Arg Thr Ser Phe Asn Arg Phe Ile Cys Leu Ala Gln 
        115                 120                 125             


Lys 
    


